Detection of Toxoplasma gondii antibody for diagnosis of ocular toxoplasmosis
نویسندگان
چکیده
منابع مشابه
Toxoplasma gondii and ocular toxoplasmosis: pathogenesis.
The protozoan Toxoplasma gondii is an obligate intracellular parasite that can infect any warm blooded animal,' as well as reptiles and fish,2' and shows a high incidence in humans, with approximately 500 million people throughout the world having antibodies to Tgondii.5 The organism is ubiquitous in nature and produces one of the most common infections ofhumans.' It is the most common cause of...
متن کاملPCR-based detection of Toxoplasma gondii DNA in blood and ocular samples for diagnosis of ocular toxoplasmosis.
PCR detection of Toxoplasma gondii in blood has been suggested as a possibly efficient method for the diagnosis of ocular toxoplasmosis (OT) and furthermore for genotyping the strain involved in the disease. To assess this hypothesis, we performed PCR with 121 peripheral blood samples from 104 patients showing clinical and/or biological evidence of ocular toxoplasmosis and from 284 (258 patient...
متن کاملThe temperature-sensitive mutants of Toxoplasma gondii and ocular toxoplasmosis.
The risk of blindness caused by ocular toxoplasmosis supports efforts to improve our understanding for control of this disease. In this study, the involvement of CD8(+), CD4(+), B cell, and IL-10 gene in the immune response of primary ocular infection with the temperature-sensitive mutant (ts-4) of the RH Toxoplasma gondii strain, and in the protective immunity of ocular ts-4 vaccination and ch...
متن کاملDiagnosis of congenital toxoplasmosis: comparison of targets for detection of Toxoplasma gondii by PCR.
Three PCR targets (18S ribosomal DNA, B1, and AF146527) and mouse inoculation were compared for 83 samples in the context of congenital toxoplasmosis. These four techniques are not statistically different in terms of sensitivity and specificity. However, further analysis highlighted problems sometimes encountered with PCR diagnosis of congenital toxoplasmosis.
متن کاملLaboratory diagnosis of Toxoplasma gondii infection and toxoplasmosis.
For the past 40 years, the Toxoplasma Serology Laboratory at the Palo Alto Medical Foundation Research Institute (TSL-PAMFRI) has been dedicated to the laboratory diagnosis of Toxoplasma gondii infection and toxoplasmosis. TSL-PAMFRI is the "brain child" of Jack S. Remington. Jack's ceaseless devotion to objectivity and uncompromising excellence has made TSL-PAMFRI the Toxoplasma reference labo...
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ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2010
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2010.02.2127